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Carotid Artery Disease: Multivariate Analysis of a Single Center in Mexico City

Received: 2 March 2022    Accepted: 14 April 2022    Published: 10 May 2022
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Abstract

Introduction. Stroke is the fourth leading cause of death in the United States and the leading cause of disability. Of these, carotid artery disease is responsible for up to 15% to 30% of strokes. The objetive is knowing the risk factors and their impact on four possible scenarios in the diagnosis and treatment of carotid artery disease. 1: significant stenosis measured by ultrasound Doppler carotid, 2: significant stenosis measured by diagnostic cerebral angiography, 3: plaque ulceration measured by angiography, and 4: carotid stent placement. Material and Methods. A retrospective study was carried out with 29 patients, 12 patients to whom was placed a carotid stent and 17 control patients, Odds ratio was calculated for risk factors: high blood pressure, diabetes, cancer, smoking and dyslipidemia. And then multivariate analysis was performed with the same variables. Results. For the risk factors with statistical significance for carotid ulcer were dyslipidemia and cancer, and for stent placement, smoking, and clinically presented as a transient ischemic attack. For the multivariate analysis, the only factor associated with stent placement was smoking. Conclusions. Of the entire range of risk factors associated with cerebrovascular disease, tobacco use is the factor most strongly associated with a patient with carotid disease ending up in endovascular treatment. So prevention or lifestyle modification is the best tool to avoid these outcomes.

Published in International Journal of Neurosurgery (Volume 6, Issue 1)
DOI 10.11648/j.ijn.20220601.13
Page(s) 11-18
Creative Commons

This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited.

Copyright

Copyright © The Author(s), 2022. Published by Science Publishing Group

Keywords

Carotid Artery Disease, Ulcerated Carotid Plaque, Carotid Stent, Transient Isquemic Attack, Stroke

References
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Cite This Article
  • APA Style

    Daniel Alejandro Vega-Moreno, José Ramón Aguilar-Calderón, María Elena Córdoba-Mosqueda, Víctor Andrés Reyes-Rodríguez, Mauricio Daniel Sánchez-Calderón, et al. (2022). Carotid Artery Disease: Multivariate Analysis of a Single Center in Mexico City. International Journal of Neurosurgery, 6(1), 11-18. https://doi.org/10.11648/j.ijn.20220601.13

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    ACS Style

    Daniel Alejandro Vega-Moreno; José Ramón Aguilar-Calderón; María Elena Córdoba-Mosqueda; Víctor Andrés Reyes-Rodríguez; Mauricio Daniel Sánchez-Calderón, et al. Carotid Artery Disease: Multivariate Analysis of a Single Center in Mexico City. Int. J. Neurosurg. 2022, 6(1), 11-18. doi: 10.11648/j.ijn.20220601.13

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    AMA Style

    Daniel Alejandro Vega-Moreno, José Ramón Aguilar-Calderón, María Elena Córdoba-Mosqueda, Víctor Andrés Reyes-Rodríguez, Mauricio Daniel Sánchez-Calderón, et al. Carotid Artery Disease: Multivariate Analysis of a Single Center in Mexico City. Int J Neurosurg. 2022;6(1):11-18. doi: 10.11648/j.ijn.20220601.13

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  • @article{10.11648/j.ijn.20220601.13,
      author = {Daniel Alejandro Vega-Moreno and José Ramón Aguilar-Calderón and María Elena Córdoba-Mosqueda and Víctor Andrés Reyes-Rodríguez and Mauricio Daniel Sánchez-Calderón and José Omar Santellán-Hernández and Diego Ochoa-Cacique and Carlos Betancourt-Quiroz and Mario Alberto Dueñas-Espinoza and Andrés Alberto Moral-Naranjo and Martha Elena González-Jiménez and Ulises García-González},
      title = {Carotid Artery Disease: Multivariate Analysis of a Single Center in Mexico City},
      journal = {International Journal of Neurosurgery},
      volume = {6},
      number = {1},
      pages = {11-18},
      doi = {10.11648/j.ijn.20220601.13},
      url = {https://doi.org/10.11648/j.ijn.20220601.13},
      eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.ijn.20220601.13},
      abstract = {Introduction. Stroke is the fourth leading cause of death in the United States and the leading cause of disability. Of these, carotid artery disease is responsible for up to 15% to 30% of strokes. The objetive is knowing the risk factors and their impact on four possible scenarios in the diagnosis and treatment of carotid artery disease. 1: significant stenosis measured by ultrasound Doppler carotid, 2: significant stenosis measured by diagnostic cerebral angiography, 3: plaque ulceration measured by angiography, and 4: carotid stent placement. Material and Methods. A retrospective study was carried out with 29 patients, 12 patients to whom was placed a carotid stent and 17 control patients, Odds ratio was calculated for risk factors: high blood pressure, diabetes, cancer, smoking and dyslipidemia. And then multivariate analysis was performed with the same variables. Results. For the risk factors with statistical significance for carotid ulcer were dyslipidemia and cancer, and for stent placement, smoking, and clinically presented as a transient ischemic attack. For the multivariate analysis, the only factor associated with stent placement was smoking. Conclusions. Of the entire range of risk factors associated with cerebrovascular disease, tobacco use is the factor most strongly associated with a patient with carotid disease ending up in endovascular treatment. So prevention or lifestyle modification is the best tool to avoid these outcomes.},
     year = {2022}
    }
    

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  • TY  - JOUR
    T1  - Carotid Artery Disease: Multivariate Analysis of a Single Center in Mexico City
    AU  - Daniel Alejandro Vega-Moreno
    AU  - José Ramón Aguilar-Calderón
    AU  - María Elena Córdoba-Mosqueda
    AU  - Víctor Andrés Reyes-Rodríguez
    AU  - Mauricio Daniel Sánchez-Calderón
    AU  - José Omar Santellán-Hernández
    AU  - Diego Ochoa-Cacique
    AU  - Carlos Betancourt-Quiroz
    AU  - Mario Alberto Dueñas-Espinoza
    AU  - Andrés Alberto Moral-Naranjo
    AU  - Martha Elena González-Jiménez
    AU  - Ulises García-González
    Y1  - 2022/05/10
    PY  - 2022
    N1  - https://doi.org/10.11648/j.ijn.20220601.13
    DO  - 10.11648/j.ijn.20220601.13
    T2  - International Journal of Neurosurgery
    JF  - International Journal of Neurosurgery
    JO  - International Journal of Neurosurgery
    SP  - 11
    EP  - 18
    PB  - Science Publishing Group
    SN  - 2640-1959
    UR  - https://doi.org/10.11648/j.ijn.20220601.13
    AB  - Introduction. Stroke is the fourth leading cause of death in the United States and the leading cause of disability. Of these, carotid artery disease is responsible for up to 15% to 30% of strokes. The objetive is knowing the risk factors and their impact on four possible scenarios in the diagnosis and treatment of carotid artery disease. 1: significant stenosis measured by ultrasound Doppler carotid, 2: significant stenosis measured by diagnostic cerebral angiography, 3: plaque ulceration measured by angiography, and 4: carotid stent placement. Material and Methods. A retrospective study was carried out with 29 patients, 12 patients to whom was placed a carotid stent and 17 control patients, Odds ratio was calculated for risk factors: high blood pressure, diabetes, cancer, smoking and dyslipidemia. And then multivariate analysis was performed with the same variables. Results. For the risk factors with statistical significance for carotid ulcer were dyslipidemia and cancer, and for stent placement, smoking, and clinically presented as a transient ischemic attack. For the multivariate analysis, the only factor associated with stent placement was smoking. Conclusions. Of the entire range of risk factors associated with cerebrovascular disease, tobacco use is the factor most strongly associated with a patient with carotid disease ending up in endovascular treatment. So prevention or lifestyle modification is the best tool to avoid these outcomes.
    VL  - 6
    IS  - 1
    ER  - 

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Author Information
  • Neurosurgery Department, Hospital Central Sur de Alta Especialidad Pemex Picacho, Mexico City, Mexico

  • Neurosurgery Department, Hospital Central Sur de Alta Especialidad Pemex Picacho, Mexico City, Mexico

  • Faculty of Medicine, University of Belgrade, Beograd, Serbia

  • Neurosurgery Department, Hospital Central Norte Petroleos Mexicanos, Mexico City, Mexico

  • Neurosurgery Department, Hospital Central Sur de Alta Especialidad Pemex Picacho, Mexico City, Mexico

  • Neurosurgery Department, Hospital Central Sur de Alta Especialidad Pemex Picacho, Mexico City, Mexico

  • Neurosurgery Department, Hospital Central Sur de Alta Especialidad Pemex Picacho, Mexico City, Mexico

  • Neurosurgery Department, Hospital Central Sur de Alta Especialidad Pemex Picacho, Mexico City, Mexico

  • Neurosurgery Department, Hospital Central Sur de Alta Especialidad Pemex Picacho, Mexico City, Mexico

  • Faculty of Medicine, National Autonomous University of Mexico, Mexico City, Mexico

  • Neurosurgery Department, Hospital Central Sur de Alta Especialidad Pemex Picacho, Mexico City, Mexico

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