Volume 2, Issue 2, December 2018, Page: 39-42
Cutaneous Carcinosarcoma of the Scalp - A Case Report and Literature Review
Hlatywayo Lawrence, Department of Neurosurgery, Faculty of Medicine, University of Zimbabwe, Harare, Zimbabwe
Nyamapfene Brighton Valentine, Department of Neurosurgery, Faculty of Medicine, University of Zimbabwe, Harare, Zimbabwe
Nathaniel Zimani, Department of Neurosurgery, Faculty of Medicine, University of Zimbabwe, Harare, Zimbabwe
Aaron Musara, Department of Neurosurgery, Faculty of Medicine, University of Zimbabwe, Harare, Zimbabwe
Khita Phiri, Department of Pathology, University of Zimbabwe, Harare, Zimbabwe
Kazadi Kalangu, Department of Neurosurgery, Faculty of Medicine, University of Zimbabwe, Harare, Zimbabwe
Rudo Makunike Mutasa, Department of Pathology, University of Zimbabwe, Harare, Zimbabwe
Received: Oct. 30, 2018;       Accepted: Nov. 12, 2018;       Published: Dec. 17, 2018
DOI: 10.11648/j.ijn.20180202.15      View  372      Downloads  55
Abstract
Carcinosarcomas are a group of biphasic tumours. They are composed of co-existing malignant epithelial and mesenchymal components. They are extremely rare in the skin. We present a case of a 43 year old female patient who came as a referral from a local district hospital with a chronic painless mass for 7 years. It had ulcerated 6 months prior to presentation with bleeding. The scalp mass was resected with a 10 mm margin. The histological diagnosis was carcinosarcoma as both carcinomatous and sarcomatous. Diagnosis of carcinosarcoma rests on demonstration of pleomorphic spindle cells with pressence of both epithelial and mesenchymal elements within the same tumour. The biphasic nature of the tumour may be seen on light microscopy showing atypical squamoid epithelial cells admixed with mucoid secreting variants as shown in our case. Immunopositivity to both cytokeratin and vimentin on a background of the described light microscopy findings confirms the diagnosis. Generally, surgery with resection of at least 10mm margin is the primary therapeutic modality. Local spread is rare. In conclusion, cutaneous carcinosarcoma of the scalp is rare and management is patient dependant with surgery being the mainstay treatment.
Keywords
Carcinosarcoma, Cutaneous Fibro-sarcoma, Surgical Resection
To cite this article
Hlatywayo Lawrence, Nyamapfene Brighton Valentine, Nathaniel Zimani, Aaron Musara, Khita Phiri, Kazadi Kalangu, Rudo Makunike Mutasa, Cutaneous Carcinosarcoma of the Scalp - A Case Report and Literature Review, International Journal of Neurosurgery. Vol. 2, No. 2, 2018, pp. 39-42. doi: 10.11648/j.ijn.20180202.15
Copyright
Copyright © 2018 Authors retain the copyright of this article.
This article is an open access article distributed under the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/) which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
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