Volume 3, Issue 1, June 2019, Page: 9-12
Perianeurysmal Edema After Embolization with Flow Diversion
Mehrnoush Gorjian, Department of Neurosurgery, Massachusetts General Hospital, Boston, USA
Scott Raymond, Department of Neurosurgery, Massachusetts General Hospital, Boston, USA
Matthew Koch, Department of Neurosurgery, Massachusetts General Hospital, Boston, USA
Aman Patel, Department of Neurosurgery, Massachusetts General Hospital, Boston, USA
Received: Jun. 23, 2019;       Accepted: Aug. 4, 2019;       Published: Aug. 19, 2019
DOI: 10.11648/j.ijn.20190301.13      View  716      Downloads  102
Flow diversion is an endovascular technique for embolization of intracranial aneurysms using a semi-porous stent to that redirects blood flow away from the aneurysm and is a scaffold for vessel remodeling. With flow diversion, aneurysms close slowly over 6-12 months as endothelial growth into the stent covers the neck of the aneurysm. Flow diversion is the preferred treatment for unruptured, large, paraclinoid aneurysms, which are otherwise challenging to treat with conventional open surgical or endovascular techniques. Post-embolization perianeurysmal edema (PAE) is an uncommon complication that occurs weeks to months after embolization and manifests as brain parenchymal edema surrounding the treated aneurysm. The clinical presentation is varied and includes headache, seizure or focal neurologic deficit. Frequently, PAE is misdiagnosed as an embolic stroke, which is a more common post-embolization complication and has some clinical and imaging overlap. PAE can be differentiated from ischemia by the absence of restricted diffusion and aneurysm wall enhancement on post-contrast Magnetic Resonance Imaging (MRI). PAE was initially described following coil embolization, but has subsequently been observed after flow diversion alone or with adjunctive coiling. Post-embolization PAE presumably results from rapid aneurysm thrombosis, endothelial cell necrosis, and the ensuing inflammatory reaction, which spreads to the adjacent brain parenchyma. Early recognition of PAE is critical to initiate appropriate therapy.
Perianeurysmal Edema, Flow Diversion Stent, Coil Embolization, Intracranial Aneurysm
To cite this article
Mehrnoush Gorjian, Scott Raymond, Matthew Koch, Aman Patel, Perianeurysmal Edema After Embolization with Flow Diversion, International Journal of Neurosurgery. Vol. 3, No. 1, 2019, pp. 9-12. doi: 10.11648/j.ijn.20190301.13
Copyright © 2019 Authors retain the copyright of this article.
This article is an open access article distributed under the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/) which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
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